changed df to adults df to extract relevant info
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5 changed files with 78 additions and 1007 deletions
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@ -3,7 +3,7 @@ getwd()
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setwd('~/git/mosaic_2020/')
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getwd()
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########################################################################
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# TASK: Extract relevant columns from mosaic data
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# TASK: Extract relevant columns from mosaic adults data
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# sam
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# serum
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# npa
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@ -14,17 +14,17 @@ getwd()
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source("read_data.R")
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# clear unnecessary variables
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#rm()
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rm(all_df)
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########################################################################
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#=========
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# sam
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#=========
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sam_regex = regex(".*_sam[1-3]{1}$", ignore_case = T)
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sam_cols_i = str_extract(colnames(all_df), sam_regex) # not boolean
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#sam_cols_b = colnames(all_df)%in%sam_cols_i # boolean
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sam_cols_i = str_extract(colnames(adult_df), sam_regex) # not boolean
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#sam_cols_b = colnames(adult_df)%in%sam_cols_i # boolean
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sam_cols = colnames(all_df)[colnames(all_df)%in%sam_cols_i]
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sam_cols = colnames(adult_df)[colnames(adult_df)%in%sam_cols_i]
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# this contains log columns + daysamp_samXX: omitting these
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sam_regex_log_days = regex("log|day.*_sam[1-3]{1}$", ignore_case = T, perl = T)
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@ -48,7 +48,7 @@ cat("Extracting SAM cols + metadata_cols")
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if ( length(sam_cols_to_extract) == length(meta_data_cols) + length(sam_cols_clean) ){
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cat("Extracing", length(sam_cols_to_extract), "columns for sam")
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sam_df = all_df[, sam_cols_to_extract]
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sam_df = adult_df[, sam_cols_to_extract]
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}else{
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cat("FAIL: length mismatch"
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, "Expeceted to extract:", length(meta_data_cols) + length(sam_cols_clean), "columns"
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@ -61,10 +61,10 @@ colnames_sam_df = colnames(sam_df); colnames_sam_df
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# serum
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#=========
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serum_regex = regex(".*_serum[1-3]{1}$", ignore_case = T)
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serum_cols_i = str_extract(colnames(all_df), serum_regex) # not boolean
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#serum_cols_b = colnames(all_df)%in%serum_cols_i # boolean
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serum_cols_i = str_extract(colnames(adult_df), serum_regex) # not boolean
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#serum_cols_b = colnames(adult_df)%in%serum_cols_i # boolean
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serum_cols = colnames(all_df)[colnames(all_df)%in%serum_cols_i]
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serum_cols = colnames(adult_df)[colnames(adult_df)%in%serum_cols_i]
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# this contains log columns + dayserump_serumXX: omitting these
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serum_regex_log_days = regex("log|day.*_serum[1-3]{1}$", ignore_case = T, perl = T)
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@ -88,7 +88,7 @@ cat("Extracting SERUM cols + metadata_cols")
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if ( length(serum_cols_to_extract) == length(meta_data_cols) + length(serum_cols_clean) ){
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cat("Extracing", length(serum_cols_to_extract), "columns for serum")
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serum_df = all_df[, serum_cols_to_extract]
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serum_df = adult_df[, serum_cols_to_extract]
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}else{
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cat("FAIL: length mismatch"
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, "Expeceted to extract:", length(meta_data_cols) + length(serum_cols_clean), "columns"
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@ -101,10 +101,10 @@ colnames_serum_df = colnames(serum_df); colnames_serum_df
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# npa
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#=========
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npa_regex = regex(".*_npa[1-3]{1}$", ignore_case = T)
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npa_cols_i = str_extract(colnames(all_df), npa_regex) # not boolean
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#npa_cols_b = colnames(all_df)%in%npa_cols_i # boolean
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npa_cols_i = str_extract(colnames(adult_df), npa_regex) # not boolean
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#npa_cols_b = colnames(adult_df)%in%npa_cols_i # boolean
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npa_cols = colnames(all_df)[colnames(all_df)%in%npa_cols_i]
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npa_cols = colnames(adult_df)[colnames(adult_df)%in%npa_cols_i]
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# this contains log columns + daynpap_npaXX: omitting these
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npa_regex_log_days = regex("log|day|vl_samptime|ct.*_npa[1-3]{1}$", ignore_case = T, perl = T)
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@ -128,7 +128,7 @@ cat("Extracting NPA cols + metadata_cols")
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if ( length(npa_cols_to_extract) == length(meta_data_cols) + length(npa_cols_clean) ){
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cat("Extracing", length(npa_cols_to_extract), "columns for npa")
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npa_df = all_df[, npa_cols_to_extract]
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npa_df = adult_df[, npa_cols_to_extract]
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}else{
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cat("FAIL: length mismatch"
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, "Expeceted to extract:", length(meta_data_cols) + length(npa_cols_clean), "columns"
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@ -137,8 +137,11 @@ if ( length(npa_cols_to_extract) == length(meta_data_cols) + length(npa_cols_cle
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colnames_npa_df = colnames(npa_df); colnames_npa_df
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#==============
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# quick checks
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#==============
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colnames_check = as.data.frame(cbind(colnames_sam_df, colnames_serum_df, colnames_npa_df))
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tail(colnames_check)
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tail(colnames_check) # gives a warning message due to differeing no. of rows for cbind!
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# put NA where a match doesn't exist
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# unmatched lengths
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@ -168,12 +171,16 @@ quick_check = as.data.frame(cbind(metadata_all$mosaic
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, metadata_all$adult
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, metadata_all$age
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, metadata_all$obesity
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, metadata_all$obese2))
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, metadata_all$obese2
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))
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colnames(quick_check) = c("mosaic", "adult", "age", "obesity", "obese2")
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##########################################################################
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# LF data
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##########################################################################
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cols_to_omit = c("adult", "obese2"
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, "height", "height_unit", "weight"
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, "weight_unit", "visual_est_bmi", "bmi_rating")
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#==============
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# lf data: sam
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@ -181,19 +188,11 @@ colnames(quick_check) = c("mosaic", "adult", "age", "obesity", "obese2")
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str(sam_df)
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table(sam_df$obesity); table(sam_df$obese2)
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sam_df_adults = sam_df[sam_df$adult == 1,]
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cols_to_omit = c("type"
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#, "flustat"
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#, "obesity"
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#, "obese2"
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, "height", "height_unit", "weight"
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, "weight_unit", "visual_est_bmi", "bmi_rating")
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#sam_df_adults_clean = sam_df_adults[!cols_to_omit]
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#sam_df_adults = sam_df[sam_df$adult == 1,] # resolved at source and only dealing wit age as adult
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sam_df_adults = sam_df
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wf_cols = colnames(sam_df_adults)[!colnames(sam_df_adults)%in%cols_to_omit]
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sam_df_adults_clean = sam_df_adults[wf_cols]
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sam_wf = sam_df_adults[wf_cols]
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pivot_cols = meta_data_cols
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# subselect pivot_cols
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@ -208,25 +207,25 @@ if (length(pivot_cols) == length(meta_data_cols) - length(cols_to_omit)){
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quit()
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}
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expected_rows_sam_lf = nrow(sam_df_adults_clean) * (length(sam_df_adults_clean) - length(pivot_cols)); expected_rows_sam_lf
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expected_rows_sam_lf = nrow(sam_wf) * (length(sam_wf) - length(pivot_cols)); expected_rows_sam_lf
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# using regex:
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sam_adults_lf = sam_df_adults_clean %>%
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sam_lf = sam_wf %>%
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tidyr::pivot_longer(-all_of(pivot_cols)
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, names_to = c("mediator", "sample_type", "timepoint")
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, names_pattern = "(.*)_(.*)([1-3]{1})"
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, values_to = "value")
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if (
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(nrow(sam_adults_lf) == expected_rows_sam_lf) & (sum(table(is.na(sam_adults_lf$mediator))) == expected_rows_sam_lf)
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(nrow(sam_lf) == expected_rows_sam_lf) & (sum(table(is.na(sam_lf$mediator))) == expected_rows_sam_lf)
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) {
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cat(paste0("PASS: long format data has correct no. of rows and NA in mediator:"
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, "\nNo. of rows: ", nrow(sam_adults_lf)
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, "\nNo. of cols: ", ncol(sam_adults_lf)))
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, "\nNo. of rows: ", nrow(sam_lf)
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, "\nNo. of cols: ", ncol(sam_lf)))
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} else{
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cat(paste0("FAIL:long format data has unexpected no. of rows or NAs in mediator"
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, "\nExpected no. of rows: ", expected_rows_sam_lf
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, "\nGot: ", nrow(sam_adults_lf)
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, "\nGot: ", nrow(sam_lf)
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, "\ncheck expected rows calculation!"))
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quit()
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}
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@ -241,11 +240,11 @@ if (
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str(serum_df)
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table(serum_df$obesity); table(serum_df$obese2)
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serum_df_adults = serum_df[serum_df$adult == 1,]
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#serum_df_adults = serum_df[serum_df$adult == 1,] # extract based on age
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serum_df_adults = serum_df
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#serum_df_adults_clean = serum_df_adults[!cols_to_omit]
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wf_cols = colnames(serum_df_adults)[!colnames(serum_df_adults)%in%cols_to_omit]
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serum_df_adults_clean = serum_df_adults[wf_cols]
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serum_wf = serum_df_adults[wf_cols]
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pivot_cols = meta_data_cols
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pivot_cols = meta_data_cols[!meta_data_cols%in%cols_to_omit];pivot_cols
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@ -259,25 +258,25 @@ if (length(pivot_cols) == length(meta_data_cols) - length(cols_to_omit)){
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quit()
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}
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expected_rows_serum_lf = nrow(serum_df_adults_clean) * (length(serum_df_adults_clean) - length(pivot_cols)); expected_rows_serum_lf
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expected_rows_serum_lf = nrow(serum_wf) * (length(serum_wf) - length(pivot_cols)); expected_rows_serum_lf
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# using regex:
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serum_adults_lf = serum_df_adults_clean %>%
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serum_lf = serum_wf %>%
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tidyr::pivot_longer(-all_of(pivot_cols)
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, names_to = c("mediator", "sample_type", "timepoint")
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, names_pattern = "(.*)_(.*)([1-3]{1})"
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, values_to = "value")
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if (
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(nrow(serum_adults_lf) == expected_rows_serum_lf) & (sum(table(is.na(serum_adults_lf$mediator))) == expected_rows_serum_lf)
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(nrow(serum_lf) == expected_rows_serum_lf) & (sum(table(is.na(serum_lf$mediator))) == expected_rows_serum_lf)
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) {
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cat(paste0("PASS: long format data has correct no. of rows and NA in mediator:"
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, "\nNo. of rows: ", nrow(serum_adults_lf)
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, "\nNo. of cols: ", ncol(serum_adults_lf)))
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, "\nNo. of rows: ", nrow(serum_lf)
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, "\nNo. of cols: ", ncol(serum_lf)))
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} else{
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cat(paste0("FAIL:long format data has unexpected no. of rows or NAs in mediator"
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, "\nExpected no. of rows: ", expected_rows_serum_lf
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, "\nGot: ", nrow(serum_adults_lf)
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, "\nGot: ", nrow(serum_lf)
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, "\ncheck expected rows calculation!"))
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quit()
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}
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@ -288,11 +287,11 @@ if (
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str(npa_df)
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table(npa_df$obesity); table(npa_df$obese2)
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npa_df_adults = npa_df[npa_df$adult == 1,]
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#npa_df_adults_clean = npa_df_adults[!cols_to_omit]
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#npa_df_adults = npa_df[npa_df$adult == 1,] # extract based on age
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npa_df_adults = npa_df
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wf_cols = colnames(npa_df_adults)[!colnames(npa_df_adults)%in%cols_to_omit]
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npa_df_adults_clean = npa_df_adults[wf_cols]
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npa_wf = npa_df_adults[wf_cols]
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pivot_cols = meta_data_cols
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pivot_cols = meta_data_cols[!meta_data_cols%in%cols_to_omit];pivot_cols
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@ -306,25 +305,25 @@ if (length(pivot_cols) == length(meta_data_cols) - length(cols_to_omit)){
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quit()
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}
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expected_rows_npa_lf = nrow(npa_df_adults_clean) * (length(npa_df_adults_clean) - length(pivot_cols)); expected_rows_npa_lf
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expected_rows_npa_lf = nrow(npa_wf) * (length(npa_wf) - length(pivot_cols)); expected_rows_npa_lf
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# using regex:
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npa_adults_lf = npa_df_adults_clean %>%
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npa_lf = npa_wf %>%
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tidyr::pivot_longer(-all_of(pivot_cols)
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, names_to = c("mediator", "sample_type", "timepoint")
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, names_pattern = "(.*)_(.*)([1-3]{1})"
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, values_to = "value")
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if (
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(nrow(npa_adults_lf) == expected_rows_npa_lf) & (sum(table(is.na(npa_adults_lf$mediator))) == expected_rows_npa_lf)
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(nrow(npa_lf) == expected_rows_npa_lf) & (sum(table(is.na(npa_lf$mediator))) == expected_rows_npa_lf)
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) {
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cat(paste0("PASS: long format data has correct no. of rows and NA in mediator:"
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, "\nNo. of rows: ", nrow(npa_adults_lf)
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, "\nNo. of cols: ", ncol(npa_adults_lf)))
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, "\nNo. of rows: ", nrow(npa_lf)
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, "\nNo. of cols: ", ncol(npa_lf)))
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} else{
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cat(paste0("FAIL:long format data has unexpected no. of rows or NAs in mediator"
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, "\nExpected no. of rows: ", expected_rows_npa_lf
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, "\nGot: ", nrow(npa_adults_lf)
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, "\nGot: ", nrow(npa_lf)
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, "\ncheck expected rows calculation!"))
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quit()
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}
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@ -334,12 +333,14 @@ if (
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rm(sam_regex, sam_regex_log_days, sam_cols, sam_cols_clean, sam_cols_i, sam_cols_to_extract, sam_cols_to_omit)
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rm(serum_regex, serum_regex_log_days, serum_cols, serum_cols_clean, serum_cols_i, serum_cols_to_extract, serum_cols_to_omit)
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rm(npa_regex, npa_regex_log_days, npa_cols, npa_cols_clean, npa_cols_i, npa_cols_to_extract, npa_cols_to_omit)
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rm(all_df)
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rm(adult_df)
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rm(colnames_check)
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rm(i, j, expected_cols, start, wf_cols, extra_cols, cols_to_omit)
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rm(i, j
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#, expected_cols
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, start, wf_cols, extra_cols, cols_to_omit)
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# rm not_clean dfs
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rm(sam_df_adults, serum_df_adults, npa_df_adults)
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# rm df containing non-adults
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# rm df
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rm(sam_df, serum_df, npa_df)
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