#!/usr/bin/env python3
# -*- coding: utf-8 -*-
"""
Created on Wed Aug 19 14:33:51 2020

@author: tanu
"""
#%% load packages
import os,sys
import subprocess
import argparse
import requests
import re
import time
from bs4 import BeautifulSoup
import pandas as pd
from pandas.api.types import is_string_dtype
from pandas.api.types import is_numeric_dtype
#%%#####################################################################
def submit_dynamut(host_url
                        , pdb_file
                        , mutation_list
                        , chain
                        , email_address
                        , prediction_url
                        , output_dir
                        , outfile_suffix
                        ):
    """
    Makes a POST request for dynamut predictions.

    @param host_url: valid host url for submitting the job
    @type string

    @param pdb_file: valid path to pdb structure
    @type string
    
    @param mutation_list: list of mutations (1 per line) of the format: {WT}<POS>{Mut}
	@type string
	        
    @param chain: single-letter(caps)
	@type chr

    @param email_address: email address to inform of results
	@type chr

	@param prediction_url: dynamut url for prediction
	@type string
       
    @param output_dir: output dir
	@type string
    
    @param outfile_suffix: to append to outfile
	@type string
    
    @return writes a .txt file containing url for the snps processed with user provided suffix in filename 
    @type string
    """
    
    with open(pdb_file, "rb") as pdb_file, open (mutation_list, "rb") as mutation_list:
        files = {"wild": pdb_file
                 , "mutation_list": mutation_list}
        body = {"chain": chain
                , "email": email_address}

        response = requests.post(prediction_url, files = files, data = body)
        print(response.status_code)
        if response.history:
            print('\nPASS: valid submission. Fetching result url')
            url_match = re.search('/dynamut/results_prediction/.+(?=")', response.text)
            url = host_url + url_match.group()
            print('\nURL for snp batch no ', str(outfile_suffix), ':', url)
            
            #===============
            # writing file: result urls
            #===============
            dynamut_temp_dir = output_dir + '/dynamut_temp' # creates a temp dir within output_dir
            if not os.path.exists(dynamut_temp_dir):
                print('\nCreating dynamut_temp in output_dir', output_dir )
                os.makedirs(dynamut_temp_dir)                    
            
            out_url_file = dynamut_temp_dir + '/dynamut_result_url_' + str(outfile_suffix) + '.txt'
            print('\nWriting output url file:', out_url_file)
            myfile = open(out_url_file, 'a')    
            myfile.write(url)
            myfile.close()
#%%#####################################################################