gene = "rpoB"
drug = "rifampicin"

aa_plip = c(429, 432, 491, 487)
aa_plip_5uhc = c(430, 452, 483, 491, 432, 433, 448, 450, 459, 487)
active_aa_pos = sort(unique(c(aa_plip, aa_plip_5uhc)))