Merge branch 'master' of github.com:tgttunstall/LSHTM_analysis
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commit
c9040cad21
21 changed files with 2132 additions and 243 deletions
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@ -15,7 +15,10 @@ library(ggplot2)
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library(data.table)
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library(dplyr)
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source("dirs.R")
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require("getopt", quietly = TRUE) #cmd parse arguments
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#========================================================
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# command line args
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#spec = matrix(c(
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@ -31,19 +34,6 @@ require("getopt", quietly = TRUE) #cmd parse arguments
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# stop("Missing arguments: --drug and --gene must both be specified (case-sensitive)")
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#}
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#========================================================
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#%% variable assignment: input and output paths & filenames
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drug = "pyrazinamide"
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gene = "pncA"
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gene_match = paste0(gene,"_p.")
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cat(gene_match)
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#=============
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# directories
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#=============
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datadir = paste0("~/git/Data")
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indir = paste0(datadir, "/", drug, "/input")
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outdir = paste0("~/git/Data", "/", drug, "/output")
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plotdir = paste0("~/git/Data", "/", drug, "/output/plots")
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#======
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# input
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#======
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@ -52,6 +42,17 @@ in_filename_params = paste0(tolower(gene), "_all_params.csv")
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infile_params = paste0(outdir, "/", in_filename_params)
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cat(paste0("Input file 1:", infile_params) )
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cat('columns based on variables:\n'
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, drug
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, '\n'
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, dr_muts_col
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, '\n'
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, other_muts_col
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, "\n"
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, resistance_col
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, '\n===============================================================')
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#%%===============================================================
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###########################
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# Read file: struct params
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@ -62,9 +63,6 @@ my_df = read.csv(infile_params, header = T)
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cat("\nInput dimensions:", dim(my_df))
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# quick checks
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#colnames(my_df)
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#str(my_df)
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###########################
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# extract unique mutation entries
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