renamed count_vars_ML previous version as such
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parent
14e655eeeb
commit
a5d22540e1
9 changed files with 336 additions and 185 deletions
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@ -1,12 +1,13 @@
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source("~/git/LSHTM_analysis/config/alr.R")
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source("~/git/LSHTM_analysis/scripts/plotting/get_plotting_dfs.R")
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source("~/git/LSHTM_analysis/scripts/plotting/plotting_colnames.R")
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#=======
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# output
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#=======
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outdir_images = paste0("~/git/Writing/thesis/images/results/", tolower(gene), "/")
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#outdir_images = paste0("/home/pub/Work/LSHTM/Thesis_Plots/pairs/")
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#cat("plots will output to:", outdir_images)
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cat("plots will output to:", outdir_images)
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custom_cor <- function(
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data,
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@ -190,7 +191,7 @@ unmasked_vals
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# Stability
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#================
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corr_ps_colnames = c(static_cols
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, "DUET"
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, "mCSM-DUET"
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, "FoldX"
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, "DeepDDG"
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, "Dynamut2"
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@ -7,8 +7,8 @@
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#=============
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# Data: Input
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#==============
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#source("~/git/LSHTM_analysis/config/embb.R")
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#source("~/git/LSHTM_analysis/scripts/plotting/get_plotting_dfs.R")
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source("~/git/LSHTM_analysis/config/embb.R")
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source("~/git/LSHTM_analysis/scripts/plotting/get_plotting_dfs.R")
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#cat("\nSourced plotting cols as well:", length(plotting_cols))
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@ -1,5 +1,4 @@
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#source("~/git/LSHTM_analysis/config/embb.R")
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#source("~/git/LSHTM_analysis/scripts/plotting/plotting_colnames.R")
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#source("~/git/LSHTM_analysis/scripts/plotting/get_plotting_dfs.R")
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my_gg_pairs=function(plot_df, plot_title
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@ -53,7 +52,7 @@ corr_plotdf = corr_data_extract(merged_df3
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aff_dist_cols = colnames(corr_plotdf)[grep("Dist", colnames(corr_plotdf))]
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static_cols = c("Log10(MAF)"
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, "Log10(OR)"
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#, "Log10(OR)"
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)
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############################################################
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#=============================================
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@ -85,7 +84,7 @@ unmasked_vals
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# Stability
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#================
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corr_ps_colnames = c(static_cols
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, "DUET"
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, "mCSM-DUET"
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, "FoldX"
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, "DeepDDG"
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, "Dynamut2"
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@ -95,7 +95,7 @@ unmasked_vals
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# Stability
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#================
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corr_ps_colnames = c(static_cols
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, "DUET"
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, "mCSM-DUET"
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, "FoldX"
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, "DeepDDG"
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, "Dynamut2"
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@ -1,6 +1,13 @@
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#source("~/git/LSHTM_analysis/config/katg.R")
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#source("~/git/LSHTM_analysis/scripts/plotting/plotting_colnames.R")
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#source("~/git/LSHTM_analysis/scripts/plotting/get_plotting_dfs.R")
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source("~/git/LSHTM_analysis/config/katg.R")
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source("~/git/LSHTM_analysis/scripts/plotting/get_plotting_dfs.R")
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#=======
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# output
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#=======
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outdir_images = paste0("~/git/Writing/thesis/images/results/", tolower(gene), "/")
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cat("plots will output to:", outdir_images)
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my_gg_pairs=function(plot_df, plot_title
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, tt_args_size = 2.5
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@ -85,7 +92,7 @@ unmasked_vals
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# Stability
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#================
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corr_ps_colnames = c(static_cols
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, "DUET"
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, "mCSM-DUET"
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, "FoldX"
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, "DeepDDG"
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, "Dynamut2"
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@ -203,6 +203,14 @@ write.csv(bar_or, paste0(outdir_stats, "katg_OR_10.csv"))
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top10_or$position[top10_or$position%in%active_aa_pos]
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# maf
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bar_maf = bar_or[order(bar_or$maf_percent
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, bar_or$ligand_distance
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# bar_or$nca_dist
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, bar_or$interface_dist
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, decreasing = T), ]
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head(bar_maf)
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#########################################################
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# closest most sig
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bar_or_lig = bar_or[bar_or$ligand_distance<10,]
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@ -7,10 +7,10 @@
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#=============
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# Data: Input
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#==============
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#source("~/git/LSHTM_analysis/config/rpob.R")
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#source("~/git/LSHTM_analysis/scripts/plotting/get_plotting_dfs.R")
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source("~/git/LSHTM_analysis/config/rpob.R")
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source("~/git/LSHTM_analysis/scripts/plotting/get_plotting_dfs.R")
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#cat("\nSourced plotting cols as well:", length(plotting_cols))
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cat("\nSourced plotting cols as well:", length(plotting_cols))
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####################################################
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class(merged_df3)
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