From 70f8a917e5dd7d126b62800f69d291bc7222fcb7 Mon Sep 17 00:00:00 2001
From: Tanushree Tunstall <tanu@tunstall.in>
Date: Mon, 10 Oct 2022 15:57:54 +0100
Subject: [PATCH] force button

---
 drug-target/server.R | 183 ++++++++++++++++++++++++-------------------
 1 file changed, 104 insertions(+), 79 deletions(-)

diff --git a/drug-target/server.R b/drug-target/server.R
index 99ffdd3..4b74b71 100644
--- a/drug-target/server.R
+++ b/drug-target/server.R
@@ -44,7 +44,110 @@ function(input, output, session) {
                      , color = "green")
       )
   })
-  
+  observeEvent(
+    {
+      input$switch_target
+      input$snp_ligand_dist
+      input$snp_nca_dist
+      input$snp_interface_dist
+      
+    },{
+      target_gene = input$switch_target
+      merged_df3 = cbind(get(paste0(input$switch_target, '_merged_df3')))
+      
+      position_max=max(merged_df3[['position']])
+      position_min=min(merged_df3[['position']])
+      min_ligand_distance=min(merged_df3$ligand_distance)
+      max_ligand_distance=max(merged_df3$ligand_distance)
+      # FIXME: these are IMPORTANT
+      # # add "pos_count" position count column
+      # merged_df3=merged_df3 %>% dplyr::add_count(position)
+      # merged_df3$pos_count=merged_df3$n
+      # merged_df3$n=NULL
+      # 
+      mutable_df3 = cbind(merged_df3)
+      
+      #### site_snp_count_bp ####
+      #mutable_df3[(mutable_df3$position>=plot_min & mutable_df3$position <=plot_max),]
+      # ligand_distance
+      # interface_dist
+      # nca_distance
+      # change to: multiple plots, all use site_snp_count_bp
+      # 4 x plots side by side, one normal (no dist. filter), 2/3 filtered by distance columns above
+      # use "subtitle text" from pos_count_bp_i.R
+      
+      # different data ranges required for SNP distances
+      snp_ligand_dist_df3    = merged_df3[merged_df3[['ligand_distance']]<input$snp_ligand_dist,]
+      if ("interface_dist" %in% colnames(merged_df3)){
+        snp_interface_dist_df3 = merged_df3[merged_df3[['interface_dist']]<input$snp_interface_dist,]
+      } else {
+        snp_interface_dist_df3 = NULL
+      }
+      
+      if ("nca_distance" %in% colnames(merged_df3)){
+        snp_nca_dist_df3       = merged_df3[merged_df3[['nca_distance']]<input$snp_nca_dist,]
+      } else {
+        snp_nca_dist_df3 = NULL
+      }
+      
+      
+      output$site_snp_count_bp = renderPlot(
+        site_snp_count_bp(
+          mutable_df3,
+          title_colour = 'black',
+          subtitle_colour = "black",
+          leg_text_size = 12,
+          axis_label_size = 12,
+          geom_ls = 4
+        )
+      )
+      output$site_snp_count_bp_ligand = renderPlot(
+        site_snp_count_bp(
+          snp_ligand_dist_df3,
+          title_colour = 'black',
+          subtitle_colour = "black",
+          leg_text_size = 12,
+          axis_label_size = 12,
+          geom_ls = 4
+        )
+      )
+      
+      # if ("interface_dist" %in% colnames(input$switch_target)) {
+      output$site_snp_count_interface = renderPlot(
+        site_snp_count_bp(
+          snp_interface_dist_df3,
+          title_colour = 'black',
+          subtitle_colour = "black",
+          leg_text_size = 12,
+          axis_label_size = 12,
+          geom_ls = 4
+        )
+      )
+      # } #else {
+      #   output$site_snp_count_interface = renderPlot(
+      #     ggplot() + annotate(x=1,y=1,"text", label="No interface data for this target")+theme_void()
+      #   )
+      # }
+      
+      output$site_snp_count_nca = renderPlot( #{
+        #if ("nca_distance" %in% colnames(input$switch_target)) {
+        site_snp_count_bp(
+          snp_nca_dist_df3,
+          title_colour = 'black',
+          subtitle_colour = "black",
+          leg_text_size = 12,
+          axis_label_size = 12,
+          geom_ls = 4
+        )
+        #   }  else {
+        #     ggplot() + annotate(x=1,y=1,"text", label="No RNA data for this target")+theme_void()
+        #   }
+        # }
+      )
+      
+    }
+  )
+      
   observeEvent(
     {
       input$display_position_range
@@ -52,9 +155,6 @@ function(input, output, session) {
       input$logoplot_colour_scheme
       input$omit_snp_count
       input$switch_target
-      input$snp_ligand_dist
-      input$snp_nca_dist
-      input$snp_interface_dist
       input$force
     },
     {
@@ -122,19 +222,6 @@ function(input, output, session) {
       updateNumericInput(session, "snp_nca_dist", min = min(merged_df3$nca_distance), max = max(merged_df3$nca_distance))
       
       
-      # different data ranges required for SNP distances
-      snp_ligand_dist_df3    = merged_df3[merged_df3[['ligand_distance']]<input$snp_ligand_dist,]
-      if ("interface_dist" %in% colnames(merged_df3)){
-        snp_interface_dist_df3 = merged_df3[merged_df3[['interface_dist']]<input$snp_interface_dist,]
-      } else {
-        snp_interface_dist_df3 = NULL
-      }
-      
-      if ("nca_distance" %in% colnames(merged_df3)){
-        snp_nca_dist_df3       = merged_df3[merged_df3[['nca_distance']]<input$snp_nca_dist,]
-      } else {
-        snp_nca_dist_df3 = NULL
-      }
       
       stability_colname      = stability_boxes_df[stability_boxes_df$stability_type==input$stability_snp_param,"stability_colname"]
       outcome_colname        = stability_boxes_df[stability_boxes_df$stability_type==input$stability_snp_param,"outcome_colname"]
@@ -242,68 +329,6 @@ function(input, output, session) {
         )
       )
       
-      #### site_snp_count_bp ####
-      #mutable_df3[(mutable_df3$position>=plot_min & mutable_df3$position <=plot_max),]
-      # ligand_distance
-      # interface_dist
-      # nca_distance
-      # change to: multiple plots, all use site_snp_count_bp
-      # 4 x plots side by side, one normal (no dist. filter), 2/3 filtered by distance columns above
-      # use "subtitle text" from pos_count_bp_i.R
-      
-      output$site_snp_count_bp = renderPlot(
-        site_snp_count_bp(
-          mutable_df3,
-          title_colour = 'black',
-          subtitle_colour = "black",
-          leg_text_size = 12,
-          axis_label_size = 12,
-          geom_ls = 4
-        )
-      )
-      output$site_snp_count_bp_ligand = renderPlot(
-        site_snp_count_bp(
-          snp_ligand_dist_df3,
-          title_colour = 'black',
-          subtitle_colour = "black",
-          leg_text_size = 12,
-          axis_label_size = 12,
-          geom_ls = 4
-        )
-      )
-      
-      # if ("interface_dist" %in% colnames(input$switch_target)) {
-      output$site_snp_count_interface = renderPlot(
-        site_snp_count_bp(
-          snp_interface_dist_df3,
-          title_colour = 'black',
-          subtitle_colour = "black",
-          leg_text_size = 12,
-          axis_label_size = 12,
-          geom_ls = 4
-        )
-      )
-      # } #else {
-      #   output$site_snp_count_interface = renderPlot(
-      #     ggplot() + annotate(x=1,y=1,"text", label="No interface data for this target")+theme_void()
-      #   )
-      # }
-      
-      output$site_snp_count_nca = renderPlot( #{
-        #if ("nca_distance" %in% colnames(input$switch_target)) {
-        site_snp_count_bp(
-          snp_nca_dist_df3,
-          title_colour = 'black',
-          subtitle_colour = "black",
-          leg_text_size = 12,
-          axis_label_size = 12,
-          geom_ls = 4
-        )
-        #   }  else {
-        #     ggplot() + annotate(x=1,y=1,"text", label="No RNA data for this target")+theme_void()
-        #   }
-        # }
-      )